Natural selection is fundamental to biology but foreign to physics. Why is it so? Can we design a simple physical system that undergoes evolution by natural selection?
Enzymes are unrivalled catalysts. Are they following special design principles? Can we make comparable artificial catalysts with programmable matter?
Evolution is a matter of information processing. How to formalize this intuition and rationalize the diversity of transmission mechanisms, from Lamarckism to sex?
Allostery is the regulation of protein activities by perturbations away from their active site. How does it work? Why is it so widespread?